Bioconjugation

Methods for Enzymatic Bioconjugation and Enzyme-Catalyzed Bioconjugation

We discuss step-by-step methods for enzymatic bioconjugation and enzyme-catalyzed bioconjugation with tyrosinase, sortase, and glutamate racemase.

3 years ago

Step-by-Step Methods for N-terminal Bioconjugation of Proteins

We discuss step by step methods for n-terminal bioconjugation of proteins including N-terminal methylation, biotinylation, acetylation, and labeling.

3 years ago

How to Use Palladium in Bioconjugation of Proteins and DNA – Step by Step

We describe how to use palladium in bioconjugation of proteins and DNA by providing step-by-step conjugation instructions and discussing applications.

3 years ago

Azide Bioconjugation Reactions – Overview & Method Guide

We discuss azide bioconjugation reactions including step-by-step instructions for performing click chemistry with and without copper. 

3 years ago

Bioconjugation of Nanoparticles – An Overview with Several Methods

We discuss methods for the bioconjugation of nanoparticles. We discuss different nanoparticles, functional groups, and methods for attaching to functional…

3 years ago

How to Choose the Right Bifunctional Crosslinkers for Conjugation Reactions

We discuss how to choose the right bifunctional crosslinkers for conjugation reactions including homobifunctional, heterobifunctional, and photoreactive linkers.

3 years ago

Common Bioconjugation Problems and Their Solutions

We discuss common bioconjugation problems related to protein, DNA, antibody, and enzyme bioconjugates and their solutions.

3 years ago

Tryptophan Bioconjugation Methods and Tools

We discuss different tryptophan bioconjugation methods including ABNO, UV crosslinking, electrochemical and photochemical reactions, and site-selective reactions.

3 years ago

DNA Bioconjugation Methods and Techniques

We discuss different DNA bioconjugation methods and applications. We discuss amine, thiol, and intercalation and site-specific bioconjugation.

3 years ago

Bioconjugation of PEGylated Nanoparticles

We discuss different methods for bioconjugation of pegylated nanoparticles including thiol and amine reactions and enzymatic conjugation reactions

3 years ago