Methods

Bioconjugation and Cellular Uptake: Tips to Maximize Uptake of Nanoparticles

We discuss how bioconjugation and cellular uptake of nanoparticles are interrelated and provide protocols and tips to maximize uptake of…

2 years ago

Protocols for Bioconjugation of Metal Complexes & Theory

We discuss different protocols for bioconjugation of metal complexes including chemoenzymatic, photochemical, and electropolymerization methods.

2 years ago

Hydrazine Bioconjugation Methods & Applications – A Step-by-Step Guide

We discuss different techniques and applications of Hydrazine Bioconjugation such as the Bioconjugation of Gold Nanoparticles and Bioimaging.

2 years ago

What are Bifunctional Chelating Agents and How You Can Use Them

We discuss different types of bifunctional chelating agents based on EDTA, DTPA, and DOTA. We also discuss protocols for using…

2 years ago

Arginine Bioconjugation Protocols and Theory

We discuss different arginine bioconjugation protocols including site-selective arginine conjugation, gas-phase conjugation, and use of APG.

3 years ago

Bioconjugation in Water – Protocols, Challenges, and Applications

We discuss bioconjugation in water of proteins, peptides, DNA, and antibodies including protocols, applications, and challenges of current strategies.

3 years ago

Lysine Conjugation Protocols and Applications

We discuss step-by-step lysine conjugation protocols as well as site-specific reactions with vinylsulfonamides, heteroaryls, and other techniques.

3 years ago

NHS Ester Bioconjugation Protocols and Detailed Overview

We discuss different NHS ester bioconjugation protocols for reactions with amines and hydroxyls. We also discuss hydrolysis and the use…

3 years ago

Bioconjugation Methods for Radiopharmaceutical Chemistry – Step by Step

We discuss step-by-step bioconjugation methods for radiopharmaceutical chemistry including chelation, pegylation, and bioorthogonal reactions.

3 years ago

Cysteine Bioconjugation Techniques and Applications

We discuss different cysteine bioconjugation techniques, applications, and step by step protocols including strategies which use palladium catalysts, vinyl heteroarenes,…

3 years ago